Absolutely Fabulous (1992)

Season 4: Episode 1

Edina, now overseeing a television production company, is slated to make a guest appearance with client Twiggy on Richard and Judy's morning television show. Patsy has been injecting Parralox, a Botox-like substance, in order to freeze her wrinkles. Edina is persuaded to try Parralox as well, but she awakens the next morning with a paralysed face. In addition to costing Saffy a government job, Edina is replaced by Katy Grin, her new business partner and Bubble's cousin, for the appearance.